A Study On Sickle Cell Disease - 3744 Words

Sickle cell disease, SCD, is an inherited autosomal recessive genetic disorder that affects 1 in 500 Americans of West African descent with one in 12 African Americans and one in 100 Hispanics being carriers (â€Å"Learning.† 2014). SCD is prevalent in individuals with origins in equatorial countries, such as central Africa, Near East, Mediterranean area, and in parts of India (McCance, 2010). Sickle cell anemia, sickle cell-thalassemia, and sickle cell-Hb C are all forms of sickle cell disease with sickle cell anemia being the most severe. Within the general population there is a 0.7% chance of two African American parents having a child with sickle cell anemia, a 1 in 800 birth risk for sickle cell-Hb C, and 1 in 1700 birth risk for sickle- cell thalassemia (2010). The incidence of sickle cell trait carriers can range from 7% to 13% in blacks and up to 45% in people from Eastern Africa. In comparison to the other forms of SCD, sickle cell anemia is present in a homozygou s form. Individuals are considered to be sickle cell trait carriers when they inherit Hb S from one parent and normal hemoglobin from the other parent, these individuals rarely present with any clinical manifestations (2010). Individuals with SCD inherit the sickle globin gene (HbS) from one parent and a normal (HbA) from the other parent. The allele for individuals with a sickle cell trait would be HbAS or AS and HbSS for those with SCD (2010). When two individuals are carriers to the defective geneShow MoreRelatedA Study On Sickle Cell Disease1560 Words   |  7 Pages Sickle-cell disease majorly affects the hemoglobin that is present in our blood. The job of hemoglobin is to help transport oxygen and carbon dioxide to and from the cells throughout our body. Hemoglobin is present specifically in our red blood cells. Each red blood cell contains two hundred and eighty million hemoglobin molecules. Red blood cells normal shape is a biconcave shape because of the lack of many organelles and a nucleus. The shape is so important to a red blood cells functioning thatRead MoreA Study On The Sickle Cell Disease962 Words   |  4 Pagesone study that dealt mainly with African-Americans, the results show how p revalent sickle-cell disease can be in black people. The higher rate of the trait can again be linked back to the monetary elements but it may not be limited only be limited to that as family ties are an important genetic factor of this disease. A study was done on the ethnicities of sickle cell infected patients in Sudan. In the study scientists tied to see the ethnic distribution of sickle cell disease. TheRead MoreA Study On Sickle Cell Disease1785 Words   |  8 PagesCHAPTER 1 INTRODUCTION Sickle Cell Disease Sickle Cell disease (SCD) is an inherited blood disorder in which abnormal hemoglobin is produced in red blood cells. The body creates sickle red blood cells, which are crescent shaped instead of the typical round shape. This shape of the sickle cells are stiff, as well as stick and because of this they tend to block blood flow in the blood vessels of the limbs and organs. This blockage will cause pain and organ damage, as well as serious infection. (NationalRead MoreA Research Study On Sickle Cell Disease1777 Words   |  8 Pages This research informs the reader about Sickle cell disease. The goal is to raise awareness by describing what the disease is and where it originated. It gives advice on how to recognize signs in a crisis and how to help prevent any further symptoms. This focus uses facts from medical websites such as Web MD and Mayo Clinic. This research highlights every thing there is to know about sickle cell disease through detailed descriptions of where it comes from, how it is passed on, what it does to theRead MoreA Research Study On Sickle Cell Disease Essay1765 Words   |  8 PagesSickle Cell Disease, also known as SCD, is a group of genetic red blood cell disorders marked by abnormalities in the hemoglobin. Hemoglobin is a protein in red blood cells made up of alpha and beta chains that helps to deliver oxygen throughout the body. Unlike normal red blood cells that have a circular, biconcave shape, sickle red blood cells have hemoglobin S which causes them to become stiff, sticky and shap ed like sickles. Usually normal red blood cells would move smoothly through small bloodRead MoreThe Probability of Inheriting a Disease Is Not Random1816 Words   |  7 Pagesprobability of inheriting a disease is not random. There are several factors that determine the chances on inheriting a disease such as race, gender, genetics, etc. A person of Caucasian decent is more likely to develop cystic fibrosis, an Asian person has a higher chance of inheriting Kawasaki disease and there is a very high rate of Sickle Cell Anemia among people of African lineage. Sickle Cell disease is inherited and it affects the anatomy of the red blood cells, resulting in a sickle shape which thenRead MorePrevalence Of Sickle Cell Anemia1639 Words   |  7 PagesEzeocha PREVALENCE OF SICKLE CELL ANEMIA IN THE UNITED STATES OF AMERICA According to Sickle Cell Disease American Association sickle cell anemia defined as an inherited blood disorder that alters red blood cells. Patients with sickle cell disease have their red blood cells contaminated with an abnormal kind of hemoglobin called the Hemoglobin S. The National Institute of Health (NIH), reports that this anomalous behaviour of the hemoglobin S reduces the red blood cell into a sickle shape which becomesRead MoreThe Treatment Of Sickle Cell Anemia1340 Words   |  6 PagesSickle cell anemia is not only about the body s number of red blood cells (or amount of hemoglobin) fallen below normal, it’s also involves splenic sequestration, vision loss, a stroke, deep vein thrombosis and pulmonary embolism, gallstones, a very rare form of kidney cancer, etc. Many different complications feed off of sickle cell anemia, if it s not one thing it s another. There is not a specific treatment for this disease to make it go away, but as I listed above there are wa ys of helpingRead MoreCoping Strategies And Techniques Among Sickle Cell Disease1195 Words   |  5 PagesOjong Bate â€Å"Coping strategies and techniques amongst people living with sickle cell Disease† Introduction: Sickle cell disease (SCD) is one of the many chronic health conditions yet to be well understood by health care professionals; hematologists included. It is an inherited genetic condition characterized by sickled shaped red blood cells, which alter their oxygen carring capacity. Sickle cell disease is passed from parents to offspring and it is characterized by numerous complications suchRead MoreAfrican American Parents With The Sickle Cell Trait1524 Words   |  7 PagesAfrican-American parents with the Sickle Cell Trait have the greatest risk of passing Sickle Cell Anemia to their offspring. In this article, sickle cell anemia is defined as a hereditary disease that destroys red blood cells by causing them take on an elongated and rigid sickle shape. In addition, a different type of hemoglobin called Hemoglobin S, is the protein in red blood cells that carry oxygen throughout the body. This protein starts to wrap around other red blood cells when oxygen is lacking to